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As a wellness enthusiast and lifestyle journalist, I’m always seeking out new developments in the world of health and well-being. Over the last few years, NAD+, a coenzyme found naturally in our bodies, has become a popular topic, praised by biohackers, wellness experts, and scientists alike. Available as an IV therapy and supplement, this ingredient has a lot of buzz on social media and is offered in many health destinations around the world. It’s beloved for its ability to improve aging, cellular energy, and vitality.

If you’re curious about what NAD+ does, this article dives into the science and benefits of the compound. Niagen Bioscience’s supplement brand Tru Niagen is the science-backed leader in NAD+ supplements, and I’ve experienced the benefits of both Niagen Plus’s Niagen NR IVs and the supplement at home. Here’s how you can benefit from increasing NAD+ in your life. 

What Is Tru Niagen?

Tru Niagen has a key active supernutrient called Niagen®. Niagen is their patented form of nicotinamide riboside (NR), a unique form of vitamin B3 found in nature only in trace amounts. Niagen is one of the most efficient precursors of nicotinamide adenine dinucleotide (NAD+), a molecule that’s essential to our bodies and energy metabolism. NAD+ declines as we age after the age of 30 and declines as much as 65 percent by the time we hit 70 years old.

Many people think of NR or Niagen as a new ingredient, but Tru Niagen entered the market in 2017 with its parent company ChromaDex being in business for almost 25 years. ChromaDex is a pioneer of the science around NR and developed the ingredient Niagen, leading the market with 50+ patents, 200+ scientific publications (including 35+ human clinical studies), and 275+ global research collaborations. 

NAD+ Boosting Supplement Tru Niagen: How It Works

When you take an NAD+ boosting supplement, you boost your body’s NAD+ levels, and if you’ve wondered how it’s synthesized in your body, this is what happens. When consumed, nicotinamide riboside is rapidly converted into NAD+ through a series of enzymatic reactions. Boosting NAD+ levels are associated with:

• Mitochondrial health and cellular energy
• Cellular repair
• Increased resilience to cellular stress
• Brain health
• Heart health (in combination with a healthy lifestyle)
• Muscle health and recovery

When I took the supplement, I noticed that I was able to keep up with long days better and experienced less of a midday slump. As someone who travels a lot and frequently crosses time zones, for short time periods, I have found that Tru Niagen helps me to feel more balanced when I’m going at a frenetic pace and helps me feel reinvigorated after a busy day, especially the next morning after taking the supplement.

NAD+ Supplement Benefits

Let’s go into more detail about the documented and user-reported benefits of Tru Niagen and NAD+: 

1. Cellular Energy

By supporting mitochondrial function, NAD+ supports ATP (cellular energy molecule) production, helping provide your cells the energy they need to get you through the day.

2. Brain Health

The brain is one of the most metabolically active organs in the body, requiring a continuous supply of energy to support its health. NAD+ helps power your brain cells to support cellular energy. 

3. Healthy Aging Effects

NAD+ levels decline with age. Since NAD+ is central to cell and DNA repair, boosting its levels can help target hallmarks of aging and support resilience against the natural aging process at the cellular level. 

4. Muscle Health

Whether it is on the trail, at the gym, or just walking around, NAD+ helps support muscle health, recovery, and repair. .

NAD-Boosting IV Before and After: What’s It Like Getting a Niagen IV

Another popular method for boosting NAD+ levels is through NAD IV therapy — an intravenous infusion that delivers NAD+ directly into the bloodstream. Unlike dietary NAD-boosting supplements, NAD IV bypasses the digestive system, which allows for more immediate absorption.

Before NAD IV therapy, patients may feel sluggish, mentally foggy, or fatigued — especially if they’re dealing with stress, illness, or age-related decline. After a session, many people report:

•          Sharper mental clarity

•          Increased physical energy

•          Mood elevation

•          Reduced cravings (especially for substances like alcohol or sugar)

•          Better sleep

I had previously tried an NAD+ IV that was not Niagen IV and the experience was relatively uncomfortable, making me feel slightly dizzy and nauseous during the process. I would like the feeling of what you feel when you tumble or fall off a bike, feeling slightly disoriented, more anxious, and on edge. It also took a relatively long time, approximately one hour and 15 minutes.

@rana.good Replying to @ninjalife4 My first NAD IV was uncomfortable but the @Tru Niagen ♬ original sound – Rana Good | Travel + Lifestyle

Niagen IV offers a quicker and more comfortable experience with superior tolerability, a 75% shorter infusion time, and a 20% increase in whole blood NAD+ levels three hours post-infusion (as measured by NAD+ dried blood spot tests).

Other NAD+ IV therapy is less efficient and often comes with a higher price tag and the need for medical supervision. Niagen IV therapy is widely available at wellness clinics, med spas, and functional medicine centers like Clean Market and Restore Hyper Wellness.

Typical costs range from $300 to $1000 per session, depending on dosage, clinic reputation, and location. A full course of therapy may involve multiple sessions, quickly adding up to thousands of dollars.

That’s where Tru Niagen’s NAD+ boosting supplements can offer a more affordable and accessible alternative, especially for daily, long-term use.

Niagen NAD+ Boosting Supplement Cost: How Much Do You Pay?

In comparison to NAD IV therapy, Tru Niagen is significantly more affordable. A 30-day supply of Tru Niagen typically costs between $49 to $116, depending on dosage (300 mg to 1000 mg per capsule). For those taking it as part of a long-term health plan, the annual cost of Tru Niagen NAD+ boosting supplements can be comparable to a single high-end NAD IV session. 

Tru Niagen supplements can easily be taken in your own home without having to make an IV appointment, which is especially convenient if you don’t live near a med spa or wellness clinic. 

Tru Niagen can also be dissolved into water when you use their Tru Niagen® 300mg Stick Packs perfect for when you’re on the go and staying hydrated. 

Should You Try Tru Niagen?

While there’s no single “miracle” solution to health and longevity, Tru Niagen is one of the most promising NAD+ boosters available today. Backed by peer-reviewed science, user testimonials, and decades of research, it offers a practical and accessible way to support your body’s natural vitality.

Whether you’re looking to energize your cells, support your health, age more gracefully, or simply optimize your everyday health, incorporating a trusted NAD+ boosting supplement like Tru Niagen could be a smart step forward.

And while NAD+ IV therapy can deliver rapid results for some, it’s not the only path. With Tru Niagen, you can access similar benefits from the comfort of your home — no needles, no clinics, and lower costs.

Want to try Tru Niagen supplements? Use my code RANA20 to make your first purchase.